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<!DOCTYPE html> <html> <head> <style> .a { background-color: lightgreen; } #b { width: 250px; height: 250px; } .c { width: 100px; height: 100px; border: 1px solid black; padding: 2px; mix-blend-mode: difference; } #d { isolation: auto; } </style> </head> <body> <h1>Change isolation with JavaScript</h1> <button onclick="myFunction()">Try it</button> <p>Click the "Try it" button to change the isolation property for the div "d".</p> <div id="b" class="a"> <div id="d"> <div class="a c">div d</div> </div> </div> <script> function myFunction() { document.getElementById("d").style.isolation = "isolate"; } </script> <p><b>Note:</b> Internet Explorer 11 and earlier versions do not support the isolation property.</p> </body> </html>